Pramodini B. Kale-Pradhan Pharm.D.

Pramodini B. Kale-Pradhan Pharm.D.


Professor (Clinical)

Office Location

EACPHS, Room 4132





Pharmacy Practice


Professor (clinical), Department of Pharmacy Practice

Pramodini B. Kale-Pradhan Pharm.D.

Degrees and Certifications

Doctor of Pharmacy, Philadelphia College of Pharmacy and Science, Philadelphia, PA

Bachelor of Science in Pharmacy, University of Wisconsin-Madision, Madision, WI

Advanced Resident in Infectious Diseases and Surgery, The University of Illinois at Chicago-College of Pharmacy

Fellow in Infectious Diseases and Surgery, The University of Illinois at Chicago-College of Pharmacy

Positions and Employment

2011-present, Professor (Clinical), Department of Pharmacy Practice, Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences
2007-present, Clinical Specialist - Infectious Diseases, St. John Hospital and Medical Center, Detroit, MI
2000-2010, Associate Professor (Clinical) Department of Pharmacy Practice, Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences
1991-2007, Clinical Specialist – Surgical Intensive Care, St. John Hospital and Medical Center, Detroit, MI
1991-2000, Assistant Professor (Clinical), Department of Pharmacy Practice, Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences

Awards and Honors

College of Pharmacy and Allied Health Professions, Excellence in Teaching Award, 2001

Externship Preceptor of the Year, 2001

Preceptor of the Year Award, Southeastern Michigan Society of Hospital Pharmacists, 2000

Preceptor of the Year Award, Hoffman LaRoche Hospital, 1998

Preceptor of the Year Award, Southeastern Michigan Society of Hospital Pharmacists, 1992-1993

Professional Memberships

Rho Chi Honor Society

Infectious Disease Society of America, 2007-present

Society of Critical Care Medicine, 2000-present

American Association of Colleges of Pharmacy, 1992-present

Southeastern Michigan Society of Hospital Pharmacists, 1991-present

American Colleges of Clinical Pharmacy, 1990-present

American Society of Hospital Pharmacists, 1982-present

Areas of Expertise

Gastroenterology; Infectious Diseases

Recent Publications

Selected Publications

McConachie SM, Wilhelm SM, Bhargava A, Kale-Pradhan PB. Biologic-Induced Infections in Inflammatory Bowel Disease: The TNF-α Antagonists. Ann Pharmacother. 2018 Jan 1:1060028018754896. doi: 10.1177/1060028018754896.

Giuliano CA, Binienda J, Kale-Pradhan PB and Fakih M. "I Never Would Have Caught That Before": Pharmacist Perceptions of Using Clinical Decision Support for Antimicrobial Stewardship in the United States. Qual Health Res. 2018 Jan 1:1049732317750863. doi: 10.1177/1049732317750863.

Lipari M, Smith AL, Wilhelm SM and Kale-Pradhan PB. Adherence to GOLD Guidelines in the Inpatient COPD Population. J Pharm Pract. 2018 Feb;31(1):29-33. doi: 10.1177/0897190017696949. Epub 2017 Mar 6.

Nickerson M, Bhargava A, Kale-Pradhan PB. Daptomycin-associated eosinophilic pneumonia with rechallenge: a case report. Int J Clin Pharmacol Ther. 2017 Apr 13. doi: 10.5414/CP202952.

McConachie S, Wilhelm SM, Kale-Pradhan PB. Biosimilars in Inflammatory Bowel Disease - Accumulating Clinical Evidence. Expert Rev Clin Pharmacol. 2017;10(4):391-400. doi: 10.1080/17512433.2017.1283983. PMID: 28095262

Kale-Pradhan PB and Wilhelm SM. Prebiotics and Probiotics. In Handbook of Non-Prescription Drugs – An Interactive Approach to Self Care 19th Ed., (Invited Chapter) 2017 –

Giuliano CA, Patel CR, Kale-Pradhan PB. Is the Combination of Piperacillin-Tazobactam and Vancomycin Associated with Development of Acute Kidney Injury? A Meta-analysis. Pharmacotherapy. 2016 Dec;36(12):1217-1228. doi: 10.1002/phar.1851.

McConachie SM, Wilhelm SM, Kale-Pradhan PB. New direct-acting antivirals in hepatitis C therapy: a review of sofosbuvir, ledipasvir, daclatasvir, simeprevir, paritaprevir, ombitasvir and dasabuvir. Expert Rev Clin Pharmacol. 2016 Feb;9(2):287-302. doi: 10.1586/17512433.2016.1129272. Epub 2016 Jan 8.

Kale-Pradhan PB, Mihaescu A, Wilhelm SM. Fluoroquinolone Sequential Therapy for Helicobacter pylori: A Meta-analysis. Pharmacotherapy. 2015;35(8):719-730. doi: 10.1002/phar.1614. [Epub ahead of print]

Lipari M and Kale-Pradhan PB. Vulnerable COPD patients with comorbidities: The role of rofumilast Therapeutics and Clinical Risk Management. 2014;10:969-976.

Wilhelm SM, Kale-Pradhan PB. Effects of proton pump inhibitors on vitamin B12. Maturitas. 2014 79:1-2. doi: 10.1016/j.maturitas.2014.06.005.

Wilhelm SM, Young J, and Kale-Pradhan PB. The Effect of Bariatric Surgery on Hypertension – A Meta Analysis. Ann Pharmacother 2014;48:674-682. DOI: 10.1177/1060028014529260

Lipari M, Benipal H, Kale-Pradhan PB. Roflumilast in the management of chronic obstructive pulmonary disease. Am J Health Syst Pharm. 2013 Dec 1;70(23):2087-95. doi: 10.2146/ajhp130114.

Wilhelm SM, Rjater RG and Kale-Pradhan PB. Perils and Pitfalls of Long-Term Effects of Proton Pump Inhibitors. Expert Rev Clin Pharmacol. 2013 Jul;6(4):443-51. doi: 10.1586/17512433.2013.811206

Kale-Pradhan PB, Zhao JJ, Palmer JR, Wilhelm SM. The role of antimicrobials in Crohn’s disease. Expert Rev. Gastroenterol. Hepatol. 2013;7:281–8. doi: 10.1586/egh.13.6)

Giuliano C, Kale-Pradhan PB, Johnson LB Early response of ceftaroline fosamil in the treatment of soft-tissue infections Expert Rev Clin Pharmacol. 2012;5(5):509-12. doi: 10.1586/ecp.12.50.

Giuliano C, Wilhelm SM, Kale-Pradhan PB. Are Proton Pump Inhibitors Associated with the Development of Community Acquired Pneumonia: A Meta-analysis. Expert Review of Clinical Pharmacology 2012; 5:337-44.

Wilhelm SM, Kale-Pradhan PB. Inflammatory Bowel Disease. In: Richardson M, Chant C, Chessman KH, Finks SW, Hemstreet BA, Hume AL, et al, eds. Pharmacotherapy Self-Assessment Program, 7th ed. Gastroenterology and Nutrition. Lenexa, KS: American College of Clinical Pharmacy. 2012:27-48.

Kale-Pradhan PB, Wilhelm SM and Johnson LB. Clinical Relevance of in vitro Resistance of Echinocandins:A Focus on Candida paripsilosis. Current Fungal Infection Reports 2012;6:107-112 DOI 10.1007/s12281-012-0087-9

Wilhelm SM. and Kale-Pradhan PB. Estimating Creatinine Clearance: A Meta-Analysis. Pharmacotherapy 2011;31(7):658–664.

Wilhelm SM, Johnson JL and Kale-Pradhan PB. Treating bugs with bugs: the role of probiotics as adjunctive therapy for Helicobacter pylori. Annals of Pharmacotherapy 2011;45:960-6.

Kale- Pradhan PB, Wilhelm SM, Johnson LB. Author response to alternative view point use of echinocandins for Candida parapsilosis infections. Pharmacotherapy 2011;31:87e-88e.

Giuliano CA, Dehoorne-Smith ML and Kale-Pradhan PB. Pancreatic Enzyme Products: Digesting the Changes. Annals of Pharmacotherapy 2011;45:658-66.

Kale-Pradhan PB, Morgan G, Wilhelm SM and Johnson LB. A Comparison of the Efficacy of Echinocandins and Non-Echinocandins in the Treatment of Candida parapsilosis: A Meta-Analysis. Pharmacotherapy 2010;30(12):1207–1213.

Wilhelm SM and Kale-Pradhan PB. The effect of arginine and omega 3 fatty acids in critically ill and surgical patients. Expert Rev. Clin. Pharmacol. 2010;3(4):459–469

Kale-Pradhan PB, Jassal H, Wilhelm SM and Cha R. The Role of Lactobacillus in the Prevention of Antibiotic-Associated Diarrhea. Pharmacotherapy 2010;30(2):119–126.

Kale-Pradhan PB and Wilhelm SM. Drug Induced Pancreatitis. In Drug Induced Diseases. James Tisdale and Douglas Miller (eds) 2nd Edition. 2010 American Society of Health System Pharmacists, Bethesda, MD, p 800-818. Major revisions made.

Research website