Timothy Louis Stemmler, Ph.D.

Current position

Professor and Director of Research, Department of Pharmaceutical Sciences
Wayne State University
259 Mack Ave, Room 3138
Detroit, MI 48201
Phone: 313-577-5712
Fax: 313-577-8777
Email: Timothy.Stemmler@wayne.edu

Previous appointments

  • Associate Professor of Biochemistry and Molecular Biology, Wayne State University, 2007-2013
  • Adjunct Associate Professor of Pharmacy, Wayne State University, 2007-2013
  • Visiting Professor, Stanford University, Stanford Synchrotron Radiation Lightsource, 2012
  • Adjunct Assistant Professor of Pharmacy, Wayne State University, 2003-2007
  • Assistant Professor of Biochemistry & Molecular Biology, Wayne State University, 2000-2007

Postdoctoral training

University of Utah, Department of Biochemistry, Salt Lake City, UT: NIH Fellow, 1996-2000
(Advisor: Wesley I. Sundquist)

Education

Ph.D.: Biophysical Chemistry, University of Michigan, Ann Arbor, MI, 1990-1996
(Advisor: James E. Penner-Hahn)

M.S.: Physical Chemistry, St. Louis University, St. Louis, MO, 1989-1990
(Advisor: Bruce A. Kowert)

B.A.: Physical Chemistry, St. Louis University, St. Louis, MO (cum laude), 1986-1989
(Advisor: Bruce A. Kowert)

Professional societies

  • Friedreich’s Ataxia Research Alliance (FARA), 2006-present
  • Society for Bioinorganic Chemistry, 2004-present
  • American Heart Association, 2002-present
  • American Chemical Society, 1992-present

Committees (active)

Department of Pharmaceutical Sciences (PS) or Biochemistry (BMB)

  • Seminar Series Director-PS, 2014-present
  • Graduate Committee-PS, 2014-present
  • Space Committee-PS, 2013-present

WSU Eugene Applebaum College of Pharmacy and Health Sciences

  • Continuous Process Improvement Committee, 2014-present           
  • Foundation Sciences Self Study Committee, 2014-present
  • College Research Committee, 2014-present
  • Pharmacy Assessment Committee, 2013-present

WSU School of Medicine

  • Cardiovascular Research Institute P&T Committee, 2011-present
  • M.D./Ph.D. Program Oversight Committee, 2004-present
  • M.D./Ph.D. Program Selection Committee, 2004-present

Wayne State University

  • Ph.D. Advisory Committee, 2014-present
  • Director of Graduate Admissions Search Committee, 2014-present
  • University Core Committee, 2013-present
  • Research Procurements Committee, 2011-present
  • Research Grant Review Committee, 2004-present

Special awards, fellowships and other honors (active in bold)

  • Director of Research for the Dept. of Pharmaceutical Sciences - 2014
  • School of Medicine Faculty Research Excellence Award, 2011
  • School of Medicine College Teaching Award, 2010
  • Career Development Award, 2011
  • Academy of Scholars, Junior Faculty Inductee, WSU, 2007
  • School of Medicine Faculty Research Excellence Award, 2006
  • School of Medicine College Teaching Award - 2005
  • Stanford University/SSRL Outstanding Research Highlight, 2004
  • American Heart Assoc. Scientist Development Award, 2001-2004
  • NIH Postdoctoral Fellowship, University of Utah, 1996-1999
  • Outstanding Graduate Student Research Award, University of Michigan, 1996
  • Rackham Conference Travel Award, University of Michigan, 1993-1995
  • Bachelor of Arts in Chemistry, cum Laude, St. Louis University, 1989
  • Leapold Marcus Undergraduate Research Award, St. Louis University, 1989
  • Eagle Scout, 1981

Teaching

External

  • “Structural Molecular Biology Summer School” Stanford University, Palo Alto, CA, 2012-present
  • “Medals in Medicine” Class, College of Charleston, Charleston, SC, 2012-present

Internal

  • PSC 7860: PSC Student Seminar, 2014-present
  • PSC 7020: Advanced Drug Discovery I (Co-Course Director), 2014-present
  • PSC 3210: Biotechnology and Therapeutics, 2014-present
  • PSC 3110: Pharmaceutical Biochemistry, 2014-present

​Research funding

Current Funding as Principal Investigator (* student trainee)
Stemmler, TL (PI, 25%)
“Structural Insights into the Function of Frataxin”
National Institutes of Health R01-DK068139-8
2011-2016 (competitive renewal funded since 2005)
Total Award (2005-2016): $3,181,954

Pain, D (Multiple PI, 15%), Stemmler, TL (MPI, 5%) Dancis, A (MPI, 25%)
“Regulation of Mitochondrial Nfs1 cysteine desulfurase”
National Institute of Health, R01 GM107542
2014-2018
Total Award: $2,432,287

Stemmler, TL (PI), Dzul, S* (Student Trainee, 100%)
“Characterizing Isu Scaffolding Protein and ISC Multiprotein Complex Structure and Function In Vitro”
National Institutes of Health F30 DK101230-01
2014-2018
Total Award: $217,970

Stemmler, TL (PI)
“XAS Characterization of Iron Active Sites in Proteins”
Stanford Synchrotron Radiation Laboratory User’s Proposal
2002-2015
Total Award: No funds, competitive access to National Laboratory

Patents

  • WO2002US23875 200220726 – In Vitro Assay for Inhibitors of HIV Capsid Formational Changes, 2002