Deepak K. Bhalla Ph.D.
EACPHS Room 2621
Acting Dean, Eugene Applebaum College of Pharmacy & Health Sciences
Associate Dean of Research
Professor of Pharmaceutical Sciences
Degrees and Certifications
Punjab University, Chandigarh, India B.Sc. Biology 1968
Punjab University, Chandigarh, India M.Sc. Cell Biology 1969
Howard University, Washington, D.C. Ph.D. Cell Biology 1976
Harvard Medical School, Boston, MA Post-doc. Cell Biology 1976-79
Positions and Employment
2016-Pres.: Acting Dean, College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI.
2010-Pres.: Assoc. Dean of Research, College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI.
2007-Pres.: Professor, Dept of Pharmaceutical Sciences, Wayne State University, Detroit, MI
2000-2001: Professor and Acting Chair, Dept of Occup. & Environ. Health Sci, Wayne State University. Detroit, MI
1998-2007: Professor, Dept. of Fund. & Appl. Sci. (Formerly Occup. & Environ. Health Sci.), Wayne State University. Joint appointment in the Dept of Pharmaceutical Sciences and Karmanos Cancer Institute. Detroit, MI
1995-1998: Assoc. Prof., Dept. of Occup. & Environ. Health Sci., Wayne State University, Detroit, MI.
1986-1995: Assoc. Prof., Dept. of Comm. & Environ. Med., University of California, Irvine, CA.
1982-1986: Asst. Prof., Dept. of Comm. & Environ. Med., University of California, Irvine, CA.
1979-1982: Assist. Res. Cell Biologist, Dept. of Medicine, University of California Medical Center and VAMC, San Francisco, CA.
Awards and Honors
2008: President, Inhalation and Respiratory Specialty Section, Society of Toxicology
1992-1997: Toxicology Study Section, National Institutes of Health.
1993-1994: Consultant, Revision of the air quality criteria document for ozone, U. S. EPA.
1994: Editorial Board, Inhalation Toxicology
1994: Study Section/Program Project Applications, NIEHS
1997: Harvard Center Grant review and site visit, NIEHS
2000: Guest Editor, Journal of Toxicology and Environmental Health
2000: Adhoc Study Section, National Institutes of Health.
2001: U.C. Davis Center Grant review and site visit, NIEHS
2001: ALTX-4 Study Section, National Institutes of Health.
1999-Pres.: Editorial Board, Journal of Toxicology and Environmental Health
2002: Harvard Center Grant review and site visit, NIEHS Consultant, Revision of the air quality criteria document for ozone, U. S. EPA
2003: Special Emphasis Panel (Study Section), NIEHS
2004-2008: Toxicology Subcommittee, National Research Council
2006: Study Section, National Institute of Neurodegenerative Diseases and disorders/NIH
2006-Pres: Editorial Board, Inhalation Toxicology
2006-2009: Vice President/President/Past President, Inhalation Specialty Section, Society of Toxicology
2011-Pres.: Associate Editor, Inhalation Toxicology
2011-Pres.: National Research Council, Committee on Toxicology
2011-Pres: National Research Council, Committee on Acute Exposure Guideline Levels
2015: NIH Study Section for Centers of Excellence in Environmental Health Disparities
Primary Research Interest
My current research is relevant to pulmonary toxicology of air pollutants and development of chronic lung disease. Studies are aimed at developing and characterizing animal models that simulate health consequences of air pollutants such as ozone (O3) and cigarette smoke in normal populations and in individuals whose lungs are compromised by a co-pollutant, infection or prior inflammation. Mechanistic studies are aimed at developing 1) early biomarkers and 2) protective measures.
Bassett, D.J.P. and Bhalla, D.K.- Inflammation and fibrosis. In Pulmonary Immunotoxicology, M. Cohen, J. Zelikoff and R. Schlesinger (Eds.). - Kluwer Academic Publishers, Norwell, MA, 127-151, 2000.
Bhalla, D.K and Gupta, S.K.. - Lung injury, inflammation and inflammatory stimuli in rats exposed to ozone. J. Tox. Environ. Health, 59:101-118, 2000.
Kleinman, M.T., Bufalino, C., Rasmussen, R., Hyde, D., Bhalla, D.K. and Mautz, W.J. - Toxicity of chemical components of ambient fine particulate matter (PM 2.5) inhaled by aged rats. J. Applied Tox., 20 (5): 357-364, 2000.
Bhalla, D.K. - Preface. - J. Tox. Environ. Health, 61 (1):1, 2000.
Bhalla, D.K. - Oxidative effects and inflammatory responses in the lung. J. Tox. Environ. Health, 61 (1):3-8, 2000.
Mautz, W.J., Kleinman, M.T., Bhalla, D.K. and Phalen, R.F. - Respiratory tract responses to repeated inhalation of an oxidant and acid gas-particle air pollutant mixture. Tox. Sci., 61: 331-341, 2001.
Bhalla, D.K. - Interactive effects of cigarette smoke and ozone in the induction of lung injury. Tox. Sci., 65: 1-3, 2002.
Bhalla, D.K., Reinhart, P.G., Bai, C. and Gupta, S.K. - Amelioration of ozone-induced lung injury by anti-tumor necrosis factor alpha. Tox. Sci. 69: 400-408, 2002.
Kleinman, M.T., - Hyde, D., Bufalino, C., Basbaum, R., Bhalla, D.K. and Mautz, W.J. Toxicity of chemical components of fine particles inhaled by aged rats: Effects of concentration. J. Air Waste Mgmt. Assoc. 53 (9): 1080 - 1087, 2003.
Bhalla, D.K. and Warheit, D. B. - Biological agents with potential for misuse: a historical perspective and defensive measures. Tox. Appl. Pharm. 199 (1): 71-84, 2004.
Bhalla, D.K. - Toxicologic effects of ozone and related photochemical oxidants: lung inflammation and permeability changes. EPA Air Quality Criteria for Ozone and Related Photochemical Oxidants. EPA. 600/R-05/004aF, I: 522-532, 2006.
Saha, S.P., Bhalla, D.K., Whayne, T.F. and Gairola, C.G. - Cigarette smoke and adverse health effects: an overview of research trends and future needs. Int. J. of Angiology. 16 (3): 77-83, 2007.
Karol, MH, Bast, C., Bhalla, D.K. et al. - Review of toxicologic and radiologic risks to military personnel from exposure to depleted uranium during and after combat. National Research Council of the National Academies, National Academy Press, 1-110, 2008.
Han, S.G., Andrews R.,Gairola C.G. and Bhalla D.K. - Acute pulmonary effects of combined exposure to carbon nanotubes and ozone in mice. Inhal Tox. 20 (4): 391-398, 2008.
Bhalla, D.K., Hirata, F, Rishi, A.K. and Gairola, C.G. - Cigarette smoke, inflammation and lung injury: A mechanistic perspective. J. Tox Environ Health. Part B, 12:45-64, 2009.
Han, S.G., Bhoopalan, V., Akinbiyi, T., Gairola C.G. and Bhalla D.K. - In utero Tobacco Smoke Exposure Alters Pulmonary Response of Newborn rats to Ozone. J. Tox Environ Health, Part A, 74: 668-677, 2011.
Bhoopalan, V., Han, S.G., Shah, M.M., Thomas, D.M. and Bhalla, D.K. Tobacco smoke modulates ozone-induced toxicity in rat lungs and central nervous system. Inhal Tox., 25 (1): 21-28, (2013).